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Mesothelioma and Asbestos Exposure People who use asbestos-containing products are at risk of ingesting or inhaling asbestos fibers. The fibers penetrate the lining of the abdomen and chest cavity which is also known as the pleura, or peritoneum. The exposure to asbestos increases the chance of developing malignant pleural mesothelioma, or peritoneal cancer throughout your lifetime. While the risk does appear to decrease after more than 40 years of exposure, even a small amount of asbestos exposure is dangerous. Age The older the person is when exposed, the higher the chance of developing mesothelioma. Mesothelioma is a disease that affects the mesothel an extremely thin layer that surrounds the major organs of the body. The cancerous cells expand in uncontrolled ways and develop into tumors. Mesothelioma is most often diagnosed in people who were exposed to asbestos through their own work or as a family member of someone who was exposed to it. Exposure to asbestos can cause mesothelioma due to the irritation of the mesothelium. Pleural mesothelioma can be found in the lungs' linings, but it can also affect the linings of the abdomen and peritoneum as well as the heart lining. Asbestos is a non-porous and long-lasting mineral. It was used in construction, insulation, and other industrial purposes until the 1980s. During this time millions of Americans were exposed to asbestos because of their work or living near someone who was exposed to asbestos. When asbestos is disturbed, it releases fibers into the air. These can be inhaled, and they are too hard for the body to break down or process. The fibers can cause irritation and even cancer in the lungs if they become stuck. The symptoms of mesothelioma typically do not show up until decades after exposure to asbestos. The symptoms are similar to those of other types of cancer and can be fatal if not treated. Mesothelioma affects men more often than women, and is the most frequently diagnosed in those who are over 45. Those who are at the most chance of developing mesothelioma as a result of workplace asbestos exposure include ship builders, miners, railroad workers and those who have handled or installed items made of asbestos. Family members of these individuals are also at a higher risk due to the fact that asbestos can be absorbed into their clothing. Smoking The longer someone is exposed to asbestos, the greater the chance of developing mesothelioma. This is due to the long time of latency that can last between 20 and 60 years from initial exposure to the disease until it is diagnosed. Mesothelioma can occur in different parts of the body depending on the type and quantity of asbestos. Pleural mesothelioma occurs in the lung's lining cavity and chest wall (the pleura). Peritoneal Mesothelioma can be found in the abdomen's lining, also known as the peritoneum. Anyone who has been exposed to asbestos most often develop mesothelioma in their chest or lungs. People who worked in the shipbuilding, power generation and construction industries are the most at risk. However, mesothelioma is also able to develop in individuals who were exposed to asbestos at home or at school. Children and spouses of asbestos-exposed workers may carry asbestos fibers from the workplace to their homes on their clothes hair, skin, and. This puts them at risk. People with mesothelioma are typically white and over the age of 65. They are also more likely to have a blue-collar job or military background. Asbestos was widely used by the United States Navy and other branches in the military due to its flame-resistant qualities. Many veterans were exposed to asbestos. Mesothelioma may develop when an individual's DNA undergoes mutations which cause cells to multiply unchecked. This could lead to the growth of tumors which eventually become mesothelioma. The disease can affect the whole body but is most prevalent in the chest and abdomen. Smoking does cause mesothelioma but it increases your risk by increasing the amount of asbestos you inhale. Therefore anyone who has been exposed to asbestos should consider quitting smoking cigarettes. In addition, a mesothelioma treatment program should include an expert in asbestos exposure and the risk factors for this type of cancer. A mesothelioma specialist who is experienced to assist them determine the best approach to treat this rare cancer. The doctor will be able determine whether a patient is eligible for immunotherapy or other experimental treatments. Asbestos Exposure Asbestos, a naturally occurring mineral, is used in a variety of items like flooring, roofing and insulation. Workers who handle, make or work with asbestos-containing materials are at high risk for exposure. Exposure to asbestos fibers in the air can cause cancer and illness. There is a long time of latency between exposure to asbestos and the first signs of symptoms, which makes it difficult to identify many asbestos diseases. Mesothelioma is the most dangerous asbestos-related disease. Mesothelioma symptoms can manifest between 20 and 60 years after asbestos exposure. The most frequent way that people are exposed to asbestos is through occupational exposure. All jobs that require asbestos handling or use, including those in manufacturing, construction, automotive mechanics, and electrical. Some people are also exposed through activities at home, such as smoking, or renovating older homes that have asbestos. The majority of mesothelioma cases are caused by asbestos inhalation. Inhaled asbestos fibers can travel to the lung, where they can cause irritation to the lining of the lungs, known as the pleura. This irritation can lead to thickened patches of pleura (pleural plates) and fibrosis within the lung. As the disease progresses, it could cause fluid accumulation in the chest cavity (pleural effusion) and ultimately to lung cancer. Akron asbestos lawsuits may also affect the tissues of other organs, such as the heart and abdomen. People who are exposed to asbestos in their work are at the highest chance of developing mesothelioma. People with a history of family members or mesothelioma or other asbestos-related diseases are also at risk. The risk of exposure to asbestos is higher if one has had more than one job in the course of their life. Smoking can increase the risk of mesothelioma, however, it can also worsen the disease for those already diagnosed. If you have a history of exposure to asbestos and have mesothelioma symptoms quitting smoking may make you healthier and improve the treatment outcome. Inform your doctor if you have been exposed to asbestos or have any new symptoms, such as abdominal pain or a shortness of breathe. They can prescribe medication or perform surgery to treat the condition. Genetics Many cancers are genetically linked, meaning that a person’s genes can increase the chances of them getting a particular disease. But mesothelioma itself does not have any genetic component. In fact exposure to asbestos is the primary factor. Asbestos fibers can enter the body by being inhaled or swallowed, and they stick to the chest's lining (the pleura) and the abdomen (the peritoneum) or around the heart (the pericardium). These loose fibers can harm the cells that comprise these small linings over time. This can lead to mesothelioma. Despite this, not every person exposed to asbestos gets mesothelioma. Researchers believe that other factors can determine if a person develops mesothelioma from asbestos exposure. This could include a person's age and gender as well as their family history of mesothelioma or other diseases, and whether they are afflicted with other risk factors such as smoking. Mesothelioma is more likely to develop in men than women. This is because men were more likely than women to have been exposed directly to asbestos while at work. Additionally, it takes between 20 to 60 years for mesothelioma to develop after a person's first exposure to asbestos. Another risk factor for mesothelioma includes having a faulty gene. In an investigation of two families with high mesothelioma rates scientists discovered that almost every member of the family carried a defective gene on the short arm of chromosome 3 This gene is called BAP 1 and regulates the way calcium moves within cells. If the gene is defective, this process is broken and calcium levels decrease. This allows asbestos to turn healthy cells into cancerous ones and cause mesothelioma. Additionally an mutated gene in the immune system of a person could increase the likelihood of developing mesothelioma after exposure to asbestos. The mutated gene results in a decrease in white blood cells. These cells are responsible for fighting cancerous cells. The kind of asbestos to which a person was exposed and their occupation can also increase a person's mesothelioma-related risk. The polio vaccine, given to children between 1940 and 1950, may also increase a person's risk of developing mesothelioma through exposure to cancer-causing SV40.